Re: tj/ion channel research/thanks Snoshoe

Posted by BiBrun on
URL: https://www.es-forum.com/Neurotransmitters-dopamine-etc-tp1552930p1553045.html

Tight junctions are never supposed to open, but there are
calcium channels that are supposed to let calcium through
the membranes when needed.

I should get some taurine... Blaylock's Excitotoxin book recommends it
but does not say dosage I don't think...
Bill

On Tue, Mar 30, 2010 at 2:21 PM, Evie <[hidden email]> wrote:

>
>
> Hi Snoshoe,
>
> I am SOOO behind in my email and I have to be off the computer for the next
> week, so incase I don't get to answer your other recent emails to me, know I
> really appreciate your sending all those links and info! I just have no
> time for awhile to read it! ;) Like you--I have to work on the computerin
> spurts, even tho I now have no problems with being on the computer. (I have
> too much going on in my life right now and add a holiday and anniversary
> party into the mix and I am really swamped. lol)
>
> Re cellular wall integrity..... Due to the tight junction permeability
> which I have (due to celiac genes and damage/other gene(s), I personally
> appear to leak calcium into cells, Snoshoe. (Thanks again for reminding me
> about the taurine last year, btw--I couldn't remember where my notes were
> and knew I needed an amino acid to go with the manganese. You saved me
> weeks in searching! I bless you everytime I take it. lol)
>
> When I began taking manganese and taurine last year, it was because I had
> done extensive searching on how to close tjs. My docs know so little on
> channelopathy that they just told me there was nothing to do for it.
> Period--don't even ask.... ;) I figured there was, if I really checked it
> out. Finally I found an obscure research paper which mentioned a study on
> rabbits in which they used manganese and taurine to get tjs which were stuck
> open to close. (Like you, I have a habit of losing my sites and haven't
> seen the study since! I was so sure I had saved it, but I had to "restore"
> my operating system just after, and I suspect it didn't restore that site!)
>
>
> I am very cautious in taking the manganese and taurine and only use it once
> or twice a week, often even less if I am not going anywhere the emfs are
> high. But it DOES seem to make a difference with my calcium leaking
> problem! I used to have instant reactions (esp autonomic nervous system
> symptoms) around emfs. That has been much better with the manganese and
> taurine. You copied an excerpt from a site which mentions tjs NOT
> opening--some of mine don't appear to close and that is what I suspect the
> manganese is working to do--close the tjs. My understanding (not that itis
> necessarily always correct!) is that, due to the tjs *not* closing, calcium
> floods the cell and I do not have the ability to maintain proper electrolyte
> balance, especially in the presence of emfs, which are known to affect tj
> permeability. I have read that this gene, which is responsible for allowing
> this celiac tj/BBB damage (referred to as the tight junction
> permeability gene--sorry Bill Bruno, I still haven't had time to look into
> its true genetic description), is thought to be present in 22 to 24% of the
> population. So that *could* (not necessarily, but potentially) mean that
> many people could have leaky tjs which *could* react like this, or in a
> similarly abnormal way.
>
> Hope to read all your interesting sites soon! Take care, Snoshoe,
> Diane
>
> --- On Sat, 3/27/10, snoshoe_2 <[hidden email]<snoshoe_2%40yahoo.com>>
> wrote:
>
> From: snoshoe_2 <[hidden email] <snoshoe_2%40yahoo.com>>
> Subject: [eSens] Re: Neurotransmitters/dopamine etc.
> To: [hidden email] <eSens%40yahoogroups.com>
> Date: Saturday, March 27, 2010, 8:04 PM
>
>
>
> Here's one, I just found, haven't even read it through, but it looks
> promising, info. wise -
>
> Electromagnetic fields, the modulation of brain tissue functions
> — A possible paradigm shift in biology
> www.emrpolicy. org/science/ forum/adey_ encneuro_ emfs.pdf
>
> It looks, at least on this end, like some of my links got messed up in
> sending, adding extra spaces, etc., but I've been getting added A's showing
> up in my messages lately too, so maybe it's a yahoo glitch? Sorry about
> that.
>
> I think the calcium, and magnesium will be what is more important in
> cellular wall integrity, where it is the potassium/sodium in and out flow
> through the cells that is also part of our problems -
>
> "Voltage-gated sodium channels open (activate) when the membrane is
> depolarized and close on repolarization (deactivate) but also on continuing
> depolarization by a process termed inactivation, which leaves the channel
> refractory, i.e., unable to open again for a period of time. In the
> "classical" fast inactivation, this time is of the millisecond range, butit
> can last much longer (up to seconds) in a different slow type of
> inactivation. " http://www.ionchann els.org/showabst ract.php?
> pmid=16183913
>
> ~ Snoshoe
>
> --- In eSens@yahoogroups. com, "furstc0404" <furstc0404@ ...> wrote:
> >
> >
> > Hi Evie
> >
> > Have you got any references about the calcium flux in and out of cells?I
> thought ion channels would be affected somehow, but
> > have not got the specifics and relationship with microwaves.
> >
> > Thanks
> >
> > Kooky
> >
> >
> > --- In eSens@yahoogroups. com, Evie <evie15422@> wrote:
> > >
> > > Hi, Snoshoe,
> > > Â
> > > Sorry to read in your previous posts how bad you have been feeling
> lately. We would never know it had you not said; your (re)searchesÂare
> impeccable. :) You are a fount of great info! ;)Â
> > > Â
> > > I was just discussing this with Stephen here earlier today:
> > > "6. Exposure to microwaves and other EMFs is known to abnormally affect
> calcium flux into and out of cells. This is also an abnormality found in
> people with CFS/ME."
> > > Â
> > > So, Stephen! Here is a good website to read on that subject! And
> it is put much better than I could explain, I am sure.
> > >
> > > Take care, Snoshoe; I so appreciate your great ability to ferret info
> (and I too regularly lose track of my websites, so I can relate to your
> frustration lol),
> > > Diane
> > >
> > > --- On Sat, 3/27/10, snoshoe_2 <snoshoe_2@> wrote:
> > >
> > >
> > > From: snoshoe_2 <snoshoe_2@>
> > > Subject: [eSens] Neurotransmitters/ dopamine etc.
> > > To: eSens@yahoogroups. com
> > > Date: Saturday, March 27, 2010, 5:34 PM
> > >
> > >
> > > Â
> > >
> > >
> > >
> > > Microwaves in regular people increase certain neurotransmitters in a
> way similar to people doing cocaine. That's why you find so many people
> literally addicted to the gadgets. They truly are experiencing "drug"
> withdrawal symptoms when they can't have their regular "fix" from their
> radiation, and start getting a little nuts.
> > >
> > > It really doesn't matter whether the source is from an electrical, or
> chemical reaction, things with the "right" frequencies will cause the same
> effects in the body. Unfortunately for us, choosing to avoid the electrical
> is increasingly difficult, so finding the mitigators to said frequencies,
> ie, extra supplements to repair weak areas, and replace ionized out
> elements, along with reducing exposure will become ever increasingly
> important.
> > >
> > > Par for the course for me, I lost a page I was sure I'd just saved,
> just a while ago, connecting interactions of I think dopamine, and MAO. It
> was interesting, the MAO B connection, since that plays into migraines as
> well. Here's the MAO part:
> > >
> > > "Generally, Monoamine Oxidase A (MAOA) prefers to metabolize
> norepinephrine (NE), serotonin (5-HT), and Dopamine (DA) (and other less
> clinically relevant chemicals). Monoamine Oxidase B, on the other hand,
> prefers to metabolize Dopamine (DA) (and other less clinically relevant
> chemicals).The differences between the substrate selectivity of the two
> enzymes are utilized clinically when treating specific disorders: Monoamine
> Oxidase A inhibitors have been used in the treatment of depression, and
> Monoamine Oxidase B inhibitors are used in the treatment of Parkinson's
> Disease." http://en.wikipedia .org/wiki/ Monoamine_ oxidase_B
> > >
> > > http://www.utexas. edu/research/ asrec/demoasrec. html Here's a quick
> little example on neurotransmitters.
> > >
> > > http://www.drugabus e.gov/NIDA_ notes/NNvol21N4/ Impacts.html -more
> detailed
> > >
> > > testing dopamine levels, and natural enhancement - http://www.integrativepsychiatry. net/dopamine. html
> > >
> > > On this next one, I'd like to know how they think the "microwaves are
> 'non-thermally' affecting", since it is heating things up and increasing
> vibration rates. Although the body does try to convert microwave into
> infrared, 'maybe' the heat is decreased by the time it hits these items, or
> the electrical effect happens so quickly, the heat hasn't hit yet?
> > >
> > > from: http://lifeenergies .com/ --
> > > ... "Reports of headache are consistent with the fact that microwaves
> non-thermally affect the dopamine-opiate system of the brain and increase
> the permeability of the blood-brain barrier. The reports of sleep
> disruption, on the other hand, are consistent with the effect of the
> radiation on rapid eye movement (REM) sleep and on melatonin levels, while
> memory impairment is consistent with the finding that microwave radiation
> targets the hippocampus.
> > >
> > > U of Toronto ... heightened probability of cracking up your car
> persists for up to 15 minutes after completing a cellphone call"....
> > >
> > > -------
> > > nextup.org/pdf/ PrPaulDoyonAreMi crowavesAtheMajo rCausalFactorInC
> fsME.pdf -
> > > from good 4 page article >
> > >
> > > 5. Microwaves have been shown in studies to induce Oxidative Damage
> leading to a decrease in Super Oxide Dimutase (SOD), catalase, glutathione,
> CoQ10 along with evidence of increased byproducts of oxidative stress to
> cell membranes, MDA. Oxidative damage has been found to be a major factorin
> CFS and people with CFS consistently found to be depleted in the above
> body's natural antioxidents.
> > >
> > > 6. Exposure to microwaves and other EMFs is known to abnormally affect
> calcium flux into and out of cells. This is also an abnormality found in
> people with CFS/ME.
> > >
> > > 16. Dopamine levels are also known to be affected by microwave
> radiation exposure. PWC have been found to often have low levels of dopamine
> with decreased dopamine being linked to depression, a symptoms also foundin
> PWC.
> > >
> > > 17. Decreases in the hormone Acetylcholine - known to be induced by
> exposure to EMR - is an abnormality also found in CFS/ME.
> > > (Now here we are back to nicotine, which binds into the acetylcholine
> receptors, which I mentioned earlier, made me think we could use more of
> that, -ac, not nicotine, lol- but perhaps nicotine binding there helps
> reduce or stop some of the emf from acting on that part of the system as
> rapidly. Perhaps emfs act on acetylcholine in the system in a slower way
> than say being exposed to certain nerve gases, which in toxic amounts
> besides seizuring can kill ya quick, they eat up the ac. )
> > >
> > > Austrailia site, maybe find resources for those of you there. Some of
> emf listings - http://www.livingno w.com.au/ component/ search/electroma
> gnetic%2Bsea/ %252F?ordering= newest&searchphr ase=all&limit= 20&areas[0]=
> content
> > >
> > > ~ Snoshoe
> > >
> > >
> > >
> > >
> > >
> > >
> > >
> > >
> > >
> > >
> > >
> > > [Non-text portions of this message have been removed]
> > >
> >
>
> [Non-text portions of this message have been removed]
>
>  
>


[Non-text portions of this message have been removed]