Posted by
Loni Rosser on
URL: https://www.es-forum.com/Re-Intravenous-glutathione-and-other-methods-tp1549845p1549854.html
Hi Ian,
Yeah I took antidepressant once & put me in bed foggy head, no energy. I could not handle it. Does Sue have her gall bladder. Mine came out in 1983 soit makes the liver have to work harder & thus age faster. Loni
--- On Thu, 7/2/09, Ian Kemp <
[hidden email]> wrote:
From: Ian Kemp <
[hidden email]>
Subject: RE: [eSens]Intravenous glutathione (and other methods)
To:
[hidden email]
Date: Thursday, July 2, 2009, 3:33 PM
Just for clarification - glutathione is more than just an antioxidant. It
is also a key part of the liver metabolism (Phase 2 detoxification - see
other messages in archive) which helps us break down various substances. If
it's missing, the body has to find an alternative pathway. If the other
pathways are exhausted, the substance can't be metabolised.
Practical example - glutathione helps to break down certain drugs including
SSRI's (antidepressants) . So when Sue was prescribed these when her glute
levels were low (unknown to us), her body couldn't handle it and she had
severe adverse reactions. Even common drugs like ibuprofen gave her
problems, whereas now she can metabolise them OK.
Ian
_____
From: eSens@yahoogroups. com [mailto:eSens@yahoogroups. com] On Behalf Of Loni
Sent: 02 July 2009 04:40
To: eSens@yahoogroups. com
Subject: Re: [eSens]Intravenous glutathione (and other methods)
Hi Kooky,
Yeah, we would die without it. Or livers would shrivel up due accumulation
of toxins. It is the most important antioxidant in our bodies. Maintains
mitochondria function, suppports immune system, keeps cells running
smoothly.
A deficiency has a devistating effect on the nervous system which in my case
is highly accurate because of the ES.
Without selenium you cannot produce Glutithione. So it is good to suppliment
with this mineral.
It is also important for DNA sythesis & repair.
Inhaling with a nebulizer is a good way to infuse it. I like injecting it.
Really easy & quick.
I agree that oral is not effective. Loni
--- On Wed, 7/1/09, furstc0404 <furstc@hotmail.
<mailto:furstc% 40hotmail. com> com> wrote:
From: furstc0404 <furstc@hotmail. <mailto:furstc% 40hotmail. com> com>
Subject: Re: [eSens]Intravenous glutathione (and other methods)
To: eSens@yahoogroups. <mailto:eSens% 40yahoogroups. com> com
Date: Wednesday, July 1, 2009, 3:22 PM
I can't remember where the results are, but they were very low, almost non
existent.
I would say that glutathione is one very important anti-oxidant, but there
are others. I read somewhere that if we are very low on glut, which is not
good news, other anti-oxidants can be very helpful.
I have to read up on this too, as low glutathione has been associated with
several degenerative diseases including cancers...
Kooky
--- In eSens@yahoogroups. com, Loni <loni326@... > wrote:
>
> What are your levels? Loni
>
> --- On Tue, 6/30/09, furstc0404 <furstc@...> wrote:
>
>
> From: furstc0404 <furstc@...>
> Subject: [eSens] Re: Sue's history - Intravenous glutathione (and other
methods)
> To: eSens@yahoogroups. com
> Date: Tuesday, June 30, 2009, 5:19 PM
>
>
>
>
>
>
>
>
>
> Thanks for detailed response, Ian.
>
> I also have the missing GSTM-1 apparently, this causes increases in ROS
and other free radicals causing debilitating symptoms/degenerati ve
illnesses, including MCS for some.
>
> To date, I have not be able to find out, if it is possible to alter the
missing gene.
>
> Several articles discuss raising glutathione is only beneficial when it is
raised.
>
> I have found nothing which mentions the mechanism by which it works when
GSTM-1 is mnissing. Or, if there are alternatives, concerning other
antioxidants.
>
> Does this mean that we are to take Glutathione for the rest of our lives,
and what would be the implications if there is the missing gene?
>
> Glutathione is a powerful detoxifier, but, there are others.
>
> Some have reacted to Glutathione, as I read on CFS boards and other, in
particular, those of us, who have suffered severe Adverse Drug Reaction,
meaning here prescribed drugs such as fluoroquinolones antibiotics or other
meds.
>
> I suppose, it might be wise to perhaps start with a nebulizer or patch,
which have been found to raise glutathione.
>
> I have been taking ImmunoPro and Vit Bs, C and selenium for a year, and
will start this again. It enables the body to manufacture its own
glutathione.
>
> Marc mentioned some other ways of rasing glutathione which are ineresting.
I read somewhere that taking milk thistle and artichokes also help raising
glut.
>
> The Functional Medical Doctor I see, fromn Belgium, says that it is
useless to try and raise glutathione if the GSTM-1 is missing. I need to
read up more on this.
>
> Unfortunatly, genomics. epigenetics, molecular medicine aand very much
very much in its infancy.
>
> More input on this discussion would be appreciated,
>
> --- In eSens@yahoogroups. com, "Ian Kemp" <ianandsue.kemp@ ...> wrote:
> >
> > Hi Kooky,
> >
> > Sue's missing gene is GSTM-1, but we didn't know this until a couple of
> > years after the glutathione IV treatments started - we just found that
they
> > worked! Sue's glutathione showed up low in a test (incidentally this
seems
> > quite a tricky test to interpet, the levels did not look that low
compared
> > with the reference but the doctor felt they were very bad and strongly
> > recommended glute). She started by taking about one IV glutathione per
week,
> > along with a cocktail of other items including B vitamins and magnesium
> > sulphate (both her Mg and sulphate were very low). After the initial
> > improvement she was able to drop to one a month and has sometimes been
able
> > to leave it several months. The relief is not just short-term - she can
> > feel the difference immediately but it then continues, and if she starts
> > getting MCS symptoms she knows it's time for a "top-up", after which she
can
> > always feel that she is able to detoxify things better.
> >
> > Unfortunately not many doctors or therapists have the facilities for IV
> > treatment. We go to the Breakspear Hospital (private) in Hemel
Hempstead,
> > so that's 20 miles north of London - not aware of anyone else in the
area
> > that does it.
> >
> > An alternative to IV is inhale glutathione using a nebuliser (like for
> > asthma); Sue is about to try this. Breakspear suggest it as an
alternative
> > and it is also recommended by Dr Martin Pall in his book on "Explaining
> > Unexplained Illnesses" (very heavy going, but certainly comprehensive
and
> > scientific). He also feels that reduced glutathione taken orally is
> > ineffective because it gets rapidly destroyed in the gut - although some
> > therapists suggest that even if only 10% survives long enough, it could
> > still have a beneficial effect.
> >
> > We know quite a lot of patients at Breakspear who have had benefits from
> > glutathione. Marc's the first person I've heard of who has had a
negative
> > reaction but - we are all different. Just because a treatment works for
> > most people doesn't mean it fits your particular metabolism. For
example,
> > Sue reacts badly to B12 and folic acid which are normally beneficial for
> > most people. Also, Breakspear offer a very wide range of treatments and
> > tests, but these can be very expensive, so watch your budget!
> >
> > Ian
> >
> > _____
> >
> > From: eSens@yahoogroups. com [mailto:eSens@ yahoogroups. com] On Behalf
Of
> > furstc0404
> > Sent: 30 June 2009 11:06
> > To: eSens@yahoogroups. com
> > Subject: [eSens] Re: Sue's history
> >
> >
> >
> >
> >
> >
> > Hi Ian:
> >
> > I have the missing genes for glutathione according to the NutriGenomics
> > testing from Genova. I have been raising glutathione gently and slowly
for a
> > year now, taking ImmunoPro, Vit C + selenium.
> >
> > I would like to have the Glut IV.
> >
> > But, as you mnetioned it is short lasting. From what I read, the effects
> > only last 4 hours, then it goes down again.
> >
> > How often did she do the IV glut? Did she test her glut level after
stopping
> > Glut IV a few months later?
> >
> > Also, how does that work, if I have the missing gene for glutathione?
> >
> > Lstly, do you of a good MD in London, UK, who administers Glut IV?
> >
> > Many thanks
> >
> > Kooky
> >
> > --- In eSens@yahoogroups. <mailto:eSens% 40yahoogroups. com> com, "Ian
Kemp"
> > <ianandsue.kemp@ > wrote:
> > >
> > > Hi Diane,
> > >
> > > Sue's liver itself is OK - it always came out all right on the basic
NHS
> > > (UK) tests which identify serious cell damage due to cirrhosis etc. It
is
> > > just the metabolic chemicals that are missing. So she was able to
function
> > > for 40 years with no sign of the underlying problems, and, thank
goodness,
> > > is also considerably better now that her glutathione and sulphate
levels
> > > have been restored - so any damage caused has (mainly) been
reversible.
> > >
> > > Ian
> > >
> > > _____
> > >
> > > From: eSens@yahoogroups. <mailto:eSens% 40yahoogroups. com> com
> > [mailto:eSens@ yahoogroups. <mailto:eSens% 40yahoogroups. com> com] On
Behalf
> > Of Evie
> > > Sent: 23 June 2009 21:50
> > > To: eSens@yahoogroups. <mailto:eSens% 40yahoogroups. com> com
> > > Subject: RE: [eSens] Marc's history
> > >
> > >
> > >
> > >
> > >
> > > hi Ian,
> > >
> > > interesting that Sue has missing genes for glutathione production.
that
> > > would seriously compromise her ability to detox! good thing she was
taking
> > > glutathione treatments! is her liver irreversibly bad or was she able
to
> > > side step that by the iv glutathione treatments?
> > >
> > > they now do routine genetic testing for celiac disease here in the
States
> > if
> > > you ask for it, but alot of genetic tests are not yet available. for
> > > instance, i don't think you can yet get a test for tj permability. if
you
> > > could, i wouldn't be in line tho, because i already know i have it
(you
> > > cannot get celiac disease without that gene; which is why family
members
> > who
> > > share cd genes can have cd or not. ones who have cd also have the tj
> > > permeability gene.)
> > >
> > > thanks for your input,
> > > diane
> > >
> > > --- On Sun, 6/21/09, Ian Kemp <ianandsue.kemp@
> > > <mailto:ianandsue. kemp%40ukgateway .net> ukgateway.net> wrote:
> > >
> > > From: Ian Kemp <ianandsue.kemp@ <mailto:ianandsue. kemp%40ukgateway
.net>
> > > ukgateway.net>
> > > Subject: RE: [eSens] Marc's history
> > > To: eSens@yahoogroups. <mailto:eSens% 40yahoogroups. com> com
> > > Date: Sunday, June 21, 2009, 7:32 PM
> > >
> > > Hi Diane,
> > >
> > > I'd definitely agree with you on the genetic component. Especially as
we
> > > have now been able to get some further genetic tests done which show
that
> > > Sue is missing a couple of key genes, including the one which controls
the
> > > usual main pathway for glutathione production. That certainly fits
with us
> > > having had to give Sue heavy IV doses of glutathione for the last 4
years,
> > > which has been a key factor in her improvement, but they wear off and
need
> > > to be repeated.
> > >
> > > The snag is that these genetic tests are still pretty new, rare and
> > > expensive. In an ideal world, this new science of "pharmacogenetics"
would
> > > be applied to test people before they were given long-term medication
such
> > > as antidepressants, to see whether they were capable of metabolising
them.
> > > But I think the medical profession in general (and the governments
that
> > > might pay for the tests) are a long way from accepting that yet. There
are
> > > a few cases of it being used (funnily enough, I saw a Readers Digest
> > article
> > > on it some time back), but usually only after someone has shown a bad
> > > unexpeted side effect and they are trying to find out why.
> > >
> > > Ian
> > >
> > > _____
> > >
> > > From: eSens@yahoogroups. com [mailto:eSens@ yahoogroups. com] On
Behalf Of
> > > Evie
> > > Sent: 21 June 2009 17:47
> > > To: eSens@yahoogroups. com
> > > Subject: RE: [eSens] Marc's history
> > >
> > > hi Ian,
> > >
> > > you wrote: "The big question for me is why people
> > > like you and Sue get ES, and I don't (nor lots of other people),
despite
> > > sitting in front of a computer screen all day for 20+ years and never
> > taking
> > > supplements. "
> > >
> > > it seems there has to be a genetic component going on, don't you
think?
> > > this is why i have thought tight junction permeability and ion channel
> > > dysfunction might be involved. about 25% of the population have the
gene
> > > for this, which roughly corresponds with the number of people with
ems,
> > mcs,
> > > celiac disease,autism, cfs, and fms combined--and all of these
disorders
> > > share commonalities. and, also, some of us start out with one of these
and
> > > end up with all of them (except autism which is age specific). but
even if
> > > tj/channel permeability turns out to not be involved, it is hard for
me to
> > > believe there is not still some genetic difference.
> > >
> > > my 2 cents,
> > > d
> > >
> > > --- On Sat, 6/20/09, Ian Kemp <ianandsue.kemp@
> > > <mailto:ianandsue. kemp%40ukgateway .net> ukgateway.net> wrote:
> > >
> > > From: Ian Kemp <ianandsue.kemp@ <mailto:ianandsue. kemp%40ukgateway
.net>
> > > ukgateway.net>
> > > Subject: RE: [eSens] Marc's history
> > > To: eSens@yahoogroups. <mailto:eSens% 40yahoogroups. com> com
> > > Date: Saturday, June 20, 2009, 11:08 PM
> > >
> > > Thanks Marc ... yes, it all figures. The big question for me is why
people
> > > like you and Sue get ES, and I don't (nor lots of other people),
despite
> > > sitting in front of a computer screen all day for 20+ years and never
> > taking
> > > supplements. It seems to be a combination of several causes that gives
too
> > > much "total load" on the body. I'd suggest that the prolonged
antibiotic
> > > treatment would have been a huge factor; can't remember whether you've
> > ever
> > > had a leaky gut test? Significant that your ES began soon after
that....
> > >
> > > Yes, lots of people seem to have had success with ALA for treating
many of
> > > the chronic diseases like MCS and ES, if the root cause for them was
> > > something other than heavy metals.
> > >
> > > Ian
> > >
> > > _____
> > >
> > > From: eSens@yahoogroups. com [mailto:eSens@ yahoogroups. com] On
Behalf Of
> > > Marc
> > > Martin
> > > Sent: 20 June 2009 21:56
> > > To: eSens@yahoogroups. com
> > > Subject: RE: [eSens] Marc's history
> > >
> > > > I guess a big question is why you might have become ES in the first
> > > > place. As you know, I believe there is a root cause to all cases,
and
> > > > it seems to be either (1) an underlying illness particularly in the
> > > > immune system, or (2) prolonged high exposure to EMF's
> > >
> > > Well, I've had pollen/dust/ cat allergies since I was a kid, I've had
> > > a computer related job (as in sitting all day in front of a computer)
> > > since the mid 1980's, I've had a mouthful of mercury amalgam fillings
for
> > > many years (with no particular precautions during most of their
> > > removals), and then in the late 1990's I had all sorts of vaccines for
> > > overseas travel followed by many bouts of viral infections which the
> > > doctors repeatedly tried to treat with months and months of
antibiotics.
> > > So pick your poison... :-)
> > >
> > > > All the very best with further treatment. I'm sure you'll be careful
> > > > with the alpha lipoic acid
> > >
> > > Oh yes, I've been reading some of the discussions on the "adult-metal-
> > > chelation", where ALA and DMSA seem to be the preferred metal
chelators.
> > > They are extremely cautious there about dosage and timing of doses.
And
> > > I do know of someone who used to be on this group who reportedly cured
> > > his ES mostly using ALA.
> > >
> > > I personally think my problem is mostly metals, given that I can
> > > hardly stand to take anything that mobilizes/chelates metals.
> > >
> > > Marc
> > >
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