Re: Zonulin

> From: Andrew McAfee <[hidden email]>
> Subject: [eSens] Zonulin
> To: [hidden email]
> Date: Wednesday, January 13, 2010, 8:49 AM
> Hi Diane,
> I cannot take credit for Mercola's language/quote from his
> article. It 
> sounds like you know a lot about this...more than me.
> Mercola described zonulin as a protein if I recall.
> I do have a hunch that somewhere along the line, vaccine
> ingredients 
> have played a role in creating the auto-immune environment
> which 
> predisposes one to celiac.
> I can't prove it yet though Dr. Carley has her research
> www.drcarley.com
> that proves vaccines cause "all auto-immune" diseases
> through the over 
> stimulation of the immune system.
>
> The short story is no vaccines and no gluten. I am doing
> well with the 
> first one but not as good as my wife on the second.
> Little by little...
> Thank you for the info.
> Andrew
>
> "Leaky Gut" Intestinal Protein Linked to Autoimmune
> Disorders
> "Researchers report that a protein called zonulin appears
> to be 
> responsible for maintaining the protective barrier in the
> small 
> intestine, and that high levels of this protein are
> associated with 
> disruptions in the barrier that allow foreign substances
> into the 
> body's tissues."
> http://articles.mercola.com/sites/articles/archive/2000/05/14/leaky-gut.aspx
>
>
> On Jan 12, 2010, at 5:43 PM, Evie wrote:
>
> > Hi, Andrew,
> >
> > Great job explaining this!  Yes, thyroid problems
> abound among 
> > people with celiac disease (caused by gluten
> intolerance).  I was 
> > hypothyroid and it actually normalized as a result of
> going gf and 
> > soy-free!  It is interesting, tho, that ALL
> auto-immune diseases 
> > abound among celiacs, not just thyroid problems. 
> It is because 
> > gluten causes the body to excrete a hormone (I believe
> it is called 
> > zonulin) which temporarily opens the tight junctions
> in the gut 
> > (this is how the gut permeability gets started). 
> Glutens also open 
> > tjs in, at least, some of the organs--it is known they
> affect the 
> > blood brain barrier, the lungs, the liver, and highly
> suspected, 
> > that they open the tjs of the heart.  Even normal
> people have this 
> > reaction to eating glutens, but among people with
> gluten 
> > intolerances, tjs open for a much longer time period
> and sometimes 
> > the tjs refuse to close altogether.
> >
> > I didn't know if you knew this about other auto-immune
> diseases 
> > being connected to eating glutens, but you really did
> a great job 
> > describing how glutens do damage.  They act the
> same way thru-out 
> > the body.  I have auto-immune TMJ, for
> instance.  My jaw surgeons 
> > went in to repair my left jaw joint and found there
> was nothing 
> > there but dead tissue--it could not be repaired. 
> They said it 
> > looked like the remains of a building that had been
> "fire-bombed"--
> > it was all gray and full of debris.  This was due
> to my body 
> > attacking glutens in or near my jaw joint.  This
> is also how it is I 
> > have so many diagnoses.  I have auto-immune
> diseases upon auto-
> > immune diseases.
> >
> > Just thought you might be interested, if you do not
> already know this.
> > Take care, Andrew.  My best to you and your
> wife,
> > Diane
> >
> >
> > --- On Mon, 1/11/10, Andrew McAfee <[hidden email]>
> wrote:
> >
> >> From: Andrew McAfee <[hidden email]>
> >> Subject: Re: [eSens] Auto Immune and Thyroid
> >> To: [hidden email]
> >> Date: Monday, January 11, 2010, 8:38 AM
> >> My wife has Hashimoto's and she
> >> believes as does Dr. Mercola that
> >> there is a Gluten Intolerance/auto-immune disease
> as well
> >> as mercury.
> >>
> >> http://articles.mercola.com/sites/articles/archive/2010/01/02/Many-Symptoms-Suggest-Sluggish-Thyroid.aspx
> >>
> >> "Gluten causes autoimmune responses in many people
> and can
> >> be
> >> responsible for Hashimoto’s thyroiditis, a
> common
> >> autoimmune thyroid
> >> condition. Approximately 30 percent of the people
> with
> >> Hashimoto’s
> >> thyroiditis have an autoimmune reaction to gluten,
> and it
> >> usually goes
> >> unrecognized.
> >>
> >> How this works is, gluten can cause your
> gastrointestinal
> >> system to
> >> malfunction, so foods you eat aren’t completely
> digested
> >> (aka Leaky
> >> Gut Syndrome[7]). These food particles can then be
> absorbed
> >> into your
> >> bloodstream where your body misidentifies them as
> antigens
> >> -- 
> >> substances that shouldn’t be there -- our body
> then
> >> produces
> >> antibodies against them.
> >>
> >> These antigens are similar to molecules in your
> thyroid
> >> gland. So your
> >> body accidentally attacks your thyroid. This is
> known as an
> >> autoimmune
> >> reaction or one in which your body actually
> attacks
> >> itself.
> >>
> >> Testing can be done for gluten and other food
> >> sensitivities, which
> >> involves measuring your IgG and IgA
> antibodies[8]."
> >>
> >>
> >>
> >>
> >>
> >> Andrew
> >>
> >>
> >>
> >>
> >>
> >>
> >> On Jan 10, 2010, at 8:21 PM, sctdh wrote:
> >>
> >>> Just want to clarify one point for those who
> like to
> >> quibble and
> >>> argue, the autoimmune thyroid has been known
> as
> >> Hashimoto's Disease.
> >>> The orginal contributions claimed about this
> newer
> >> author is to
> >>> break that down into a more detailed
> understanding.
> >>>
> >>>
> >>>
> >>> ------------------------------------
> >>>
> >>> Yahoo! Groups Links
> >>>
> >>>
> >>>
> >>
> >>
> >>
> >> ------------------------------------
> >>
> >> Yahoo! Groups Links
> >>
> >>
> >>     [hidden email]
> >>
> >>
> >>
> >
> >
> >
> >
> >
> > ------------------------------------
> >
> > Yahoo! Groups Links
> >
> >
> >
>
>
>
> ------------------------------------
>
> Yahoo! Groups Links
>
>
>     [hidden email]
>
>
>

> Hi, Andrew,
>
> You write:
>> Mercola described zonulin as a protein if I recall.
>> I do have a hunch that somewhere along the line, vaccine
>> ingredients
>> have played a role in creating the auto-immune environment
>> which
>> predisposes one to celiac.
>
> My reply:
> You are correct re zonulin being a protein--I mis-wrote when I  
> called it a hormone. I know a bit about zonulin and zot ("zonulin  
> occult toxin", which is what causes the brain damage in some people  
> with celiac disease), as I have followed medical research studies  
> concerning them since Dr Fasano first made the zonulin and zot/
> gluten connection in 2000, (which was also when I was dxed with  
> CD). I think there's more here than meets the eye, too (regarding  
> your thoughts on vaccines)--but I think the vacine issue is possibly  
> related to the tight junction permeability gene dysfunction. I  
> notice that I do not do well on vaccines. I come down with whatever  
> I am being immunized for, even tho doctors claim these are not live  
> viruses. But, like I mentioned yesterday, if one's blood-brain  
> barrier is leaky, we are not getting the same amount of vaccine as a  
> normal person would be getting; we are getting more. At least more  
> to our brains; it would be
> interesting to know how this, then, would then affect the immune  
> system.
>
> My best to you and your wife,
> Diane
>
> --- On Wed, 1/13/10, Andrew McAfee <[hidden email]> wrote:
>
>> From: Andrew McAfee <[hidden email]>
>> Subject: [eSens] Zonulin
>> To: [hidden email]
>> Date: Wednesday, January 13, 2010, 8:49 AM
>> Hi Diane,
>> I cannot take credit for Mercola's language/quote from his
>> article. It
>> sounds like you know a lot about this...more than me.
>> Mercola described zonulin as a protein if I recall.
>> I do have a hunch that somewhere along the line, vaccine
>> ingredients
>> have played a role in creating the auto-immune environment
>> which
>> predisposes one to celiac.
>> I can't prove it yet though Dr. Carley has her research
>> www.drcarley.com
>> that proves vaccines cause "all auto-immune" diseases
>> through the over
>> stimulation of the immune system.
>>
>> The short story is no vaccines and no gluten. I am doing
>> well with the
>> first one but not as good as my wife on the second.
>> Little by little...
>> Thank you for the info.
>> Andrew
>>
>> "Leaky Gut" Intestinal Protein Linked to Autoimmune
>> Disorders
>> "Researchers report that a protein called zonulin appears
>> to be
>> responsible for maintaining the protective barrier in the
>> small
>> intestine, and that high levels of this protein are
>> associated with
>> disruptions in the barrier that allow foreign substances
>> into the
>> body's tissues."
>> http://articles.mercola.com/sites/articles/archive/2000/05/14/leaky-gut.aspx
>>
>>
>> On Jan 12, 2010, at 5:43 PM, Evie wrote:
>>
>>> Hi, Andrew,
>>>
>>> Great job explaining this! Yes, thyroid problems
>> abound among
>>> people with celiac disease (caused by gluten
>> intolerance). I was
>>> hypothyroid and it actually normalized as a result of
>> going gf and
>>> soy-free! It is interesting, tho, that ALL
>> auto-immune diseases
>>> abound among celiacs, not just thyroid problems.
>> It is because
>>> gluten causes the body to excrete a hormone (I believe
>> it is called
>>> zonulin) which temporarily opens the tight junctions
>> in the gut
>>> (this is how the gut permeability gets started).
>> Glutens also open
>>> tjs in, at least, some of the organs--it is known they
>> affect the
>>> blood brain barrier, the lungs, the liver, and highly
>> suspected,
>>> that they open the tjs of the heart. Even normal
>> people have this
>>> reaction to eating glutens, but among people with
>> gluten
>>> intolerances, tjs open for a much longer time period
>> and sometimes
>>> the tjs refuse to close altogether.
>>>
>>> I didn't know if you knew this about other auto-immune
>> diseases
>>> being connected to eating glutens, but you really did
>> a great job
>>> describing how glutens do damage. They act the
>> same way thru-out
>>> the body. I have auto-immune TMJ, for
>> instance. My jaw surgeons
>>> went in to repair my left jaw joint and found there
>> was nothing
>>> there but dead tissue--it could not be repaired.
>> They said it
>>> looked like the remains of a building that had been
>> "fire-bombed"--
>>> it was all gray and full of debris. This was due
>> to my body
>>> attacking glutens in or near my jaw joint. This
>> is also how it is I
>>> have so many diagnoses. I have auto-immune
>> diseases upon auto-
>>> immune diseases.
>>>
>>> Just thought you might be interested, if you do not
>> already know this.
>>> Take care, Andrew. My best to you and your
>> wife,
>>> Diane
>>>
>>>
>>> --- On Mon, 1/11/10, Andrew McAfee <[hidden email]>
>> wrote:
>>>
>>>> From: Andrew McAfee <[hidden email]>
>>>> Subject: Re: [eSens] Auto Immune and Thyroid
>>>> To: [hidden email]
>>>> Date: Monday, January 11, 2010, 8:38 AM
>>>> My wife has Hashimoto's and she
>>>> believes as does Dr. Mercola that
>>>> there is a Gluten Intolerance/auto-immune disease
>> as well
>>>> as mercury.
>>>>
>>>> http://articles.mercola.com/sites/articles/archive/2010/01/02/Many-Symptoms-Suggest-Sluggish-Thyroid.aspx
>>>>
>>>> "Gluten causes autoimmune responses in many people
>> and can
>>>> be
>>>> responsible for Hashimoto’s thyroiditis, a
>> common
>>>> autoimmune thyroid
>>>> condition. Approximately 30 percent of the people
>> with
>>>> Hashimoto’s
>>>> thyroiditis have an autoimmune reaction to gluten,
>> and it
>>>> usually goes
>>>> unrecognized.
>>>>
>>>> How this works is, gluten can cause your
>> gastrointestinal
>>>> system to
>>>> malfunction, so foods you eat aren’t completely
>> digested
>>>> (aka Leaky
>>>> Gut Syndrome[7]). These food particles can then be
>> absorbed
>>>> into your
>>>> bloodstream where your body misidentifies them as
>> antigens
>>>> --  
>>>> substances that shouldn’t be there -- our body
>> then
>>>> produces
>>>> antibodies against them.
>>>>
>>>> These antigens are similar to molecules in your
>> thyroid
>>>> gland. So your
>>>> body accidentally attacks your thyroid. This is
>> known as an
>>>> autoimmune
>>>> reaction or one in which your body actually
>> attacks
>>>> itself.
>>>>
>>>> Testing can be done for gluten and other food
>>>> sensitivities, which
>>>> involves measuring your IgG and IgA
>> antibodies[8]."
>>>>
>>>>
>>>>
>>>>
>>>>
>>>> Andrew
>>>>
>>>>
>>>>
>>>>
>>>>
>>>>
>>>> On Jan 10, 2010, at 8:21 PM, sctdh wrote:
>>>>
>>>>> Just want to clarify one point for those who
>> like to
>>>> quibble and
>>>>> argue, the autoimmune thyroid has been known
>> as
>>>> Hashimoto's Disease.
>>>>> The orginal contributions claimed about this
>> newer
>>>> author is to
>>>>> break that down into a more detailed
>> understanding.
>>>>>
>>>>>
>>>>>
>>>>> ------------------------------------
>>>>>
>>>>> Yahoo! Groups Links
>>>>>
>>>>>
>>>>>
>>>>
>>>>
>>>>
>>>> ------------------------------------
>>>>
>>>> Yahoo! Groups Links
>>>>
>>>>
>>>> [hidden email]
>>>>
>>>>
>>>>
>>>
>>>
>>>
>>>
>>>
>>> ------------------------------------
>>>
>>> Yahoo! Groups Links
>>>
>>>
>>>
>>
>>
>>
>> ------------------------------------
>>
>> Yahoo! Groups Links
>>
>>
>> [hidden email]
>>
>>
>>
>
>
>
>
>
>
>
> ------------------------------------
>
> Yahoo! Groups Links
>
>
>