Possible biomarker for ES susceptibility?

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Possible biomarker for ES susceptibility?

bbin37
Hi all,

I ran across this on the Amalgam list and thought it may be of
interest to us as well since it appears mercury amalgam / thimerisol
neurotoxicity features prominently in many ES etiologies.

There was a study published in 2003 in the Journal of Alzheimer's
Disease, called "Apolipoprotein E genotyping as a potential biomarker
for mercury neurotoxicity." Here is a tinyURL to an abstract of that
article:

http://tinyurl.com/yw8o

from this study, it appears as though people with the Apolipoprotein E
epsilon-4 gene allele can't excrete metals like those with the
epsilon-2 or -3 allele, and are especially at risk for buildup of Hg
in the brain. So having this allele could predispose someone to
faster rates of Hg uptake than others in the populace and, thus,
create greater susceptibility to Hg-based pathologies like ES.

This is a possible reason why some of us get ES and others don't. And
it may have some bearing on how much more chelation is needed for
those with the epsilon-4 allele to successfully treat their ES.

Beau