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CLA appears to be safe and nontoxic at supplemental levels. However,
using evening primrose oil as a supplement for linoleic acid can cause
symptoms of undiagnosed temporal lobe epilepsy and should be used with
caution in patients with a history of epilepsy.
CLA may cause gastrointestinal upset in isolated cases, and
evening primrose oil can cause minor gastrointestinal upset and
headache.
http://findarticles.com/p/articles/mi_g2603/is_0004/ai_2603000490/Linoleic acid is believed to be helpful because myelin is composed of
lecithin, which is made of linoleic and other fatty acids.
Patients supplementing
with linoleic acid show a smaller increase in disability and reduced
severity and duration of attacks than those with no linoleic acid
supplement.
Evening primrose oil is beneficial because of its
specialized fatty-acid content, including linoleic acid. Doses of
sunflower seed oil or evening primrose oil to provide 17 grams linoleic
acid per day may be beneficial.
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